While we've been focused on the US as of late, the EU prohibition machinery is grinding on to severely hamstring e-cigarettes in Europe. One of the many limitations that is likely to get railroaded through parliament is the upward limit of 20mg/ml of nicotine in e-liquid. This decision was based on research by Dr. Fasalinos. According to a recent blog post, the EU got it all wrong.
SANCO recently decided that 20mg/ml nicotine levels should be the highest level present in the liquids of e-cigarettes. To justify this decision, they have released a document (reference 1) where they have cited two medical studies performed by me as principle researcher (references 2 and 3). The Commission suggests that my research shows that 20mg/mlnicotine limit is equivalent to the nicotine delivered through the use of tobacco cigarettes and is sufficient for most smokers to completely substitute smoking.
Since my studies are the only scientific evidence quoted by SANCO, it is my duty to inform you that the interpretation of my research is completely wrong.
Turns out the actual equivalent is 50mg/ml. That's quite a bit more than many vapers use, but may be what's necessary to help smokers make a transition.